The Denver Broncos battled through the first six games of the season and emerged with a 4-2 record and are poised for a midseason run if they can find life in their offense. The Arizona Cardinals are coming off a pretty big win of their own last week and are looking to play spoiler for Broncos Country on Sunday.
According to FanDuel, the Broncos are 4.5-point road favorites against the Cardinals in Week 7. The over/under is at 43.5 for this matchup.
Broncos vs. Betting Odds Cardinals
Denver Broncos vs. Arizona Cardinals
Sunday, October 25, 2026 at 2:05 PM Mile High time
State Farm Stadium in Glendale, Arizona
ATS Betting Lines: Denver -4.5
Moneyline Odds: Denver -230 / Arizona +190
Over/under: 43.5
The Cardinals looked pretty awful after their opening day win over the Los Angeles Chargers, though. They gave up 31, 36, 36, and 45 points in four straight losses before shocking the Los Angeles Rams on Sunday. If Denver gets the defense that played before last week, Bo Nix and the offense should be happy.
But that opens up the other side of the problems — Denver’s offense. Nix has taken a beating in recent weeks and while he is at fault, there are more problems with this offense than just him. He’s at least taking care of the football and not getting a bad sack. The Broncos need to find a run game and maybe that will help them find a more confident Nix in the passing game. Hopefully we’ll see that start this week.
What are your predictions for the Broncos-Cardinals game in Week 7?