There is a one-week reprieve of international games on the Week 8 NFL schedule as all your NFL bets are on domestic matchups. Among them are some contests that we may see again come the postseason like Ravens vs. Bills (-3), Vikings vs. Lions (-3.5), Chiefs vs. Broncos (+1.5) and Bears vs. Seahawks (-3). Meanwhile, one of the Week 8 NFL spreads stands out as the Patriots give Miami 7 points. If this NFL line holds, it would make the Pats the third biggest road favorite of the season as the Dolphins are one of two home dogs returning NFL picks. Visit our Kalshi promo code review and get $55 bonus after $25+ in trades with Kalshi promo code CBSSPORTS55:
Other games with big lines in each Week 8 NFL odds include Bengals vs. Titans (+11.5), Jaguars vs. Colts (+10) and Rams vs. Chargers (+6.5). All that Los Angeles battle was with the Chargers as visitors in their own stadium, as the team sought its first win and first shutout. The Chargers are the only winless team against the spread, while every team has at least two ATS losses this season. All updated Week 8 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and NFL predictions you need to make today’s best Week 8 NFL picks.
The model, which simulates every NFL game 10,000 times, has raised more than $5,000 for $100 players on betting sites on top-rated NFL picks since its inception. The model enters Week 8 of the 2026 NFL season with a 58-51 run over top-rated picks dating back to 2024. Anyone following its picks on NFL betting sites can see strong returns.
Now, it turns its attention to the latest Week 8 NFL odds and NFL betting lines and locked in bets for every NFL matchup. Go here to see each selection.
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Top Week 8 NFL predictions
We can tell you one of the model’s strongest Week 8 NFL picks for best betting apps is the Steelers (-3.5, 39.5) covered at home against the Browns. “At home” was the key phrase as Pittsburgh’s riding one of the best active streaks in pro sports in the Steel City against Cleveland. The Steelers have won 22 straight games at home against the Browns, a streak that dates back to 2004. This year, Pittsburgh is one of three teams 3-0 ATS at home, while the Browns are 2-2 ATS on the road. The No. Cleveland’s 28 scoring offense can’t keep up with a Steelers team that puts up 30-plus points in back-to-back home games while covering Pittsburgh more than 60% of the time. See which other teams will be selected here.
Another one of its Week 8 NFL predictions: the Rams (-6.5, 45.5) covers against the Chargers at 4:05 pm ET in more than 50% of sims. The league’s last winless team, the Chargers snapped a nine-game losing streak last year, with Justin Herbert having twice as many turnovers (12) as touchdowns (6) during that span. Jim Harbaugh’s squad is winless against the line in this nine, while Sean McVay and co. is 6-2 against the spread in non-conference games since 2025. That’s the second-best spread record in the NFL, as the Rams have had a touchdown-plus victory, with the Over hitting over 60% of the time. See which other teams will be selected here.
How to make Week 8 NFL picks
The model also calls out who will win and covers every other game on the Week 8 NFL schedule and just revealed seven teams expected to win by double digits, potentially giving you a big payday on alternate lines. You can only get every pick for every game on SportsLine.
So what Week 8 NFL picks can you make with confidence, and which seven teams should you lock down right now? Check out the latest NFL odds below, then visit SportsLine to see which teams will win and cover the spread, all from a proven computer model that has returned more than $5,000, and find out.
Week 8 NFL betting odds, lines, spreads, scores
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